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UNDATED (AP) — The top team in the NBA’s Eastern Conference knocked off the best in the West.

The Philadelphia 76ers blew a 12-point, fourth-quarter lead before Tobias Harris swished a jumper with two seconds left to give them a 107-106 win over the Los Angeles Lakers. The jumper ended a 13-0 run and allowed the Sixers to improve to 13-6.

Harris scored 24 points, Joel Embiid finished with 28 and Ben Simmons provided 17 points, 11 rebounds and 10 assists.

LeBron James scored 34 and Anthony Davis had 23 for the Lakers, who dropped behind Utah for the league’s best record.

Checking out Wednesday’s other NBA action:

— The Jazz ran their winning streak into double digits as Rudy Gobert had seasons high of 29 points and 20 rebounds in a 116-104 downing of the Mavericks. Joe Ingles also had a strong game with a season-high 21 points, all on 3-pointers. The Jazz played without leading scorer Donovan Mitchell after he entered the NBA concussion protocol.

— Giannis Antetokounmpo had 24 points, 18 rebounds and nine assists for the Bucks in a 115-108 decision over the Raptors. Khris Middleton also contributed 24 points and Brook Lopez added 20 for Milwaukee.

— Kevin Durant scored 32 points and James Harden came close to a triple-double to carry the Nets past the Hawks, 132-128 in overtime. Harden chipped in 31 points, 15 assists and eight rebounds for Brooklyn, which also received 26 points from Kyrie Irving.

— Nikola Jokic had 21 points and 11 rebounds as the Nuggets won their fifth straight, building a 25-point halftime lead in a 109-82 romp over the Heat. Michael Porter Jr. scored 17 points and JaMychal Green added 15 as Denver improved to 4-0 on its five-game road trip.

— DeMar DeRozan dropped in 21 points and Keldon Johnson added 18 with 10 rebounds as the Spurs earned their second straight home win, 110-106 against the Celtics. LaMarcus Aldridge added 20 points and Dejounte Murray had 11 points and 11 rebounds to help San Antonio end Boston’s two-game winning streak.

— Doug McDermott had 28 points and Domantas Sabonis registered a triple-double in the Pacers’ 116-106 win against the Hornets. Sabonis shot 9-for-10 and finished with 22 points, 11 rebounds and 10 assists in Indiana’s third win in four games.

— Rookie James Wiseman came off the Warriors bench to score 22 points in 23 minutes of a 121-108 victory against the Timberwolves. Kelly Oubre Jr. contributed 20 points and nine boards despite playing in early foul trouble.

— The Thunder posted a 102-97 win over the Suns as Al Horford had 21 points and 11 rebounds in the victory. Shai Gilgeous-Alexander also scored 21 points to help Oklahoma City withstand Chris Paul’s season-high 32 points in his first game against the team that traded him last summer.

— The Cavaliers came away with a 122-107 win over the Pistons as Andre Drummond had 23 points, 16 rebounds and five steals. Collin Sexton scored 29 points in helping Cleveland stop a two-game skid and move back to .500 at 9-9.

— Buddy Hield drained seven 3-pointers while scoring a season-best 29 points as the Kings whipped the Magic, 121-107. Richaun Holmes had 20 points and 12 rebounds for his third double-double of the season.

— Zion Williamson and Brandon Ingram each scored a season-high 32 points to highlight the Pelicans’ 124-106 thrashing of the Wizards. Bradley Beal almost single-handedly kept Washington in striking distance with 47 points.